
WEIGHT: 63 kg
Bust: E
One HOUR:90$
Overnight: +60$
Sex services: Food Sex, Anal Play, Striptease pro, Fetish, Massage erotic
We reported that chow-fed, adult-onset, hepatocyte-specific, GH receptor knockdown aHepGHRkd mice rapidly within 7 days develop steatosis associated with increased hepatic de novo lipogenesis DNL , independent of changes in systemic metabolic function.
In this study, we report that 6 months after induction of aHepGHRkd early signs of NASH develop, which include hepatocyte ballooning, inflammation, signs of mild fibrosis, and elevated plasma alanine aminotransferase.
These changes occur in the presence of enhanced systemic lipid utilization, without evidence of white adipose tissue lipolysis, indicating that the liver injury that develops after aHepGHRkd is due to hepatocyte-specific loss of GH signaling and not due to secondary defects in systemic metabolic function.
Most users should sign in with their email address. If you originally registered with a username please use that to sign in. To purchase short term access, please sign in to your Oxford Academic account above.
Don't already have an Oxford Academic account? Oxford University Press is a department of the University of Oxford. It furthers the University's objective of excellence in research, scholarship, and education by publishing worldwide. Sign In or Create an Account.